Title | Formation and properties of magnetic chains for 100 nm nanoparticles used in separations of molecules and cells. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Wilson RJ, Hu W, Fu CWong Po, Koh ALeen, Gaster RS, Earhart CM, Fu A, Heilshorn SC, Sinclair R, Wang SX |
Journal | J Magn Magn Mater |
Volume | 321 |
Issue | 10 |
Pagination | 1452-1458 |
Date Published | 2009 May 1 |
ISSN | 0304-8853 |
Abstract | Optical observations of 100 nm metallic magnetic nanoparticles are used to study their magnetic field induced self assembly. Chains with lengths of tens of microns are observed to form within minutes at nanoparticle concentrations of 10(10) per mL. Chain rotation and magnetophoresis are readily observed, and SEM reveals that long chains are not simple single particle filaments. Similar chains are detected for several 100 nm commercial bio-separation nanoparticles. We demonstrate the staged magnetic condensation of different types of nanoparticles into composite structures and show that magnetic chains bind to immunomagnetically labeled cells, serving as temporary handles which allow novel magnetic cell manipulations. |
DOI | 10.1016/j.jmmm.2009.02.066 |
Alternate Journal | J Magn Magn Mater |
PubMed ID | 20161001 |
PubMed Central ID | PMC2757286 |
Grant List | U54 CA119367 / CA / NCI NIH HHS / United States U54 CA119367-01 / CA / NCI NIH HHS / United States U54 CA119367-02 / CA / NCI NIH HHS / United States |