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Portable Biomarker Detection with Magnetic Nanotags.

TitlePortable Biomarker Detection with Magnetic Nanotags.
Publication TypeJournal Article
Year of Publication2010
AuthorsHall DA, Wang SX, Murmann B, Gaster RS
JournalConf Proc (Midwest Symp Circuits Syst)
Pagination1779-1782
Date Published2010 Aug 3
ISSN1548-3746
Abstract

This paper presents a hand-held, portable biosensor platform for quantitative biomarker measurement. By combining magnetic nanoparticle (MNP) tags with giant magnetoresistive (GMR) spin-valve sensors, the hand-held platform achieves highly sensitive (picomolar) and specific biomarker detection in less than 20 minutes. The rapid analysis and potential low cost make this technology ideal for point-of-care (POC) diagnostics. Furthermore, this platform is able to detect multiple biomarkers simultaneously in a single assay, creating a promising diagnostic tool for a vast number of applications.

DOI10.1109/ISCAS.2010.5537639
Alternate JournalConf Proc (Midwest Symp Circuits Syst)
PubMed ID22495252
PubMed Central IDPMC3321410
Grant ListU54 CA119367 / CA / NCI NIH HHS / United States
U54 CA119367-01 / CA / NCI NIH HHS / United States
U54 CA143907-04 / CA / NCI NIH HHS / United States