Submitted by Nuvia A. Pacheco on Tue, 02/10/2015 - 23:54
| Title | Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Fu A, Hu W, Xu L, Wilson RJ, Yu H, Osterfeld SJ, Gambhir SS, Wang SX |
| Journal | Angew Chem Int Ed Engl |
| Volume | 48 |
| Issue | 9 |
| Pagination | 1620-4 |
| Date Published | 2009 |
| ISSN | 1521-3773 |
| Keywords | Aptamers, Nucleotide, Biosensing Techniques, Magnetics, Microscopy, Electron, Scanning, Nanoparticles, Proteins |
| Abstract | Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle-protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion. |
| DOI | 10.1002/anie.200803994 |
| Alternate Journal | Angew. Chem. Int. Ed. Engl. |
| PubMed ID | 19156803 |
| PubMed Central ID | PMC2665302 |
| Grant List | 1K99 EB008558-01 / EB / NIBIB NIH HHS / United States 1U54 CA119367-01 / CA / NCI NIH HHS / United States K99 EB008558-01 / EB / NIBIB NIH HHS / United States U54 CA119367 / CA / NCI NIH HHS / United States U54 CA119367-01 / CA / NCI NIH HHS / United States |
