Using PCR and microfluidics, we plan to validate an 11 gene transcript profile, recently discovered using a “Big Data” approach, that predicts influenza vaccine responsiveness. We will explore the underlying biology of the pathways we have discovered and will translate the assay to a sensitive and rapid new platform that uses Giant MagnetoResistive Sensors.
Principal Investigators: PJ Utz, Shan X. Wang, Purvesh Khatri, Mark M. Davis
